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Grade (Inflammatory cell density, cells/mm2)
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0
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No inflammation
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1, mild
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Individual inflammatory cells (< 100 cells/mm2)
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2. moderate
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Confluent sheets of inflammatory cells without tissue destruction or lymphoid follicle formation (100–500 cells/mm2)
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3, severe
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Confluent sheets of inflammatory cells with tissue destruction or lymphoid follicle formation (> 500 cells/mm2)
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Extent (Tissue area involved by inflammatory cell infiltrates)
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1, focal
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< 10%
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2, multifocal
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10–50%
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3, diffuse
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> 50%
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- Grading scales used to score inflammatory changes in prostate and urinary bladder. The procedure for determination of grade and extent of inflammation was adapted from Inamura et al. [21]