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Table 2 Results of subgroup analyses and accuracy of leucocyte-esterase in urine dipsticks in the diagnosis of urinary tract infections or bacteriuria. (subgroups of studies without information about the study characteristic at issue are not shown) (no. of studies: 35)

From: The urine dipstick test useful to rule out infections. A meta-analysis of the accuracy

Study characteristic N Sensitivity(95%CI) Specificity(95%CI) DOR(95%CI)
POPULATION#     
   non-urological 33 0.62 (0.54–0.71) 0.70 (0.60–0.81) 9 (6 – 12)
   urological 2 0.86 (0.68–1.00) 0.93 (0.81–1.00) 276 (2 – 41974)
NON-UROLOGICAL STUDIES (N = 33)     
DISEASE#     
   bacteriuria 8 0.56 (0.38–0.82) 0.61 (0.41–0.90) 5 (5 – 8)
   UTI 25 0.64 (0.56–0.74) 0.73 (0.63–0.85) 11 (6 – 19)
SETTING     
   family physician 6 0.87 (0.83–0.92) 0.36 (0.21–0.64) 5 (2 – 28)
   outpatient 12 0.50 (0.35–0.68) 0.80 (0.72–0.88) 8 (5 – 12)
   emergency 3 0.56 90.41–0.75) 0.86 (0.74–0.99) 14 (2 – 119)
   inpatient 11 0.66 (0.60–0.73) 0.81 (0.74–0.88) 11 (8 – 16)
LEVEL OF CARE     
   community 1 0.63 (0.08–1.00) 0.85 (0.82–0.88) 9 (1 – 72)
   primary care 10 0.76 (0.60–0.98) 0.46 (0.32–0.68) 6 (3 – 11)
   secondary care 8 0.48 (0.33–0.71) 0.83 (0.73–0.93) 8 (4 – 14)
   tertiary care 14 0.62 (0.55–0.70) 0.84 (0.80–0.89) 13 (8 – 20)
READER OF TEST     
   family physician 2 0.86 (0.71–1.00) 0.17 (0.04–0.62) 2 (0.3 – 10)
   nurse 7 0.67 (0.58–0.79) 0.65 (0.37–1.00) 7 (4 – 10)
   clinician 2 0.34 (0.18–0.64) 0.90 (0.68–1.00) 7 (0.5 – 87)
   lab worker 17 0.59 (0.47–0.73) 0.81 (0.76–0.87) 11 (7 – 18)
  1. DOR: diagnostic odds ratio; #: DOR significantly different between subgroups